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Chloride

Proper name Chloride
Category Mineral (electrolyte)
Functions Chloride is one of the 3 electrolytes along with sodium and potassium. The electrolytes help maintain normal distribution of water by maintaining osmotic pressure. Chloride also helps to maintain the acid/alkaline (pH) balance in conjunction with phosphate and sulfate ions. Chloride is an essential part of hydrochloric acid (HCL). HCL is necessary for protein digestion in the stomach. And to stimulate the secretion of pancreatic bicarbonate and digestive enzymes. Chloride ions are needed to transport carbon dioxide (CO2) through the blood as bicarbonate, to the lungs for excretion. Along with the other electrolytes, chloride, calcium and magnesium are required for nerve conduction and muscle relaxation/contraction.
RDA Infants, 180 to 300 mg. Children, 350 to 750 mg. Adults, 750 mg.
Therapeutic dose Chloride is widely available in foods and thus is not supplemented.
Deficiency symptoms Chloride deficiency is rare, as it is present in so many foods, particularly salt. Deficiency can be caused by adrenal insufficiency, prolonged use of diuretics, excessive sweating, prolonged diarrhea or vomiting, or systemic acidosis. Metabolic acidosis can result from chloride deficiency. The symptoms are diarrhea, vomiting and sweating. Other symptoms of chloride deficiency include weakness, poor digestion, loss of appetite, and hair loss.
Toxicity Chloride is so efficiently excreted in the urine that toxicity and side effects have not been reported.
Best forms  Widely available in animal and vegetable foods. Supplementation is not recommended. A bioavailable form of chloride is miso, tamari or sea salt.
Food sources Chloride is present in nearly all foods, most commonly as sodium chloride (table salt).
Lab tests Serum chloride.
Drug interactions None noted.
Nutrient interactions Normally found combined with sodium as table salt.
Metabolism

Chlorine exists in the body as chloride. It accounts for about 3% of the total of the minerals in the body. It is most highly concentrated in the spinal fluid and in the gastric secretion, hydrochloric acid. 85% of chloride exists outside the cells, in the intercellular fluids.



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