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Beta-Carotene

Proper name Beta-Carotene
Category Pro Vitamin
Functions Beta-carotene stops chain reactions of lipid peroxidation by trapping free radicals. It is the nutrient most effective in quenching singlet oxygen radicals in the human body. Consumption of beta-carotene lowers the risk of many types of cancer.
RDA An RDA has not been established.
Therapeutic dose 25,000 to 50,000 International Units per day is common.
Deficiency symptoms Since beta-carotene is the precursor to vitamin A, deficiency symptoms are the same as for vitamin A.
Toxicity There is no known toxicity associated with beta-carotene however, excessive ingestion of beta-carotene may result in yellow-orange coloring of the skin, particularly the palms and soles. This effect disappears over time when the excessive dose is discontinued.
Best forms  In food. Beta-carotene is abundant in fresh green, yellow, orange or red vegetables and fruits. In the natural state, beta-carotene is associated with many other nutritional cofactors. In fact, there are over 500 carotenoids (similar plant compounds) in nature. Presumably, these have as yet unknown value in maintaining health. As a supplement, micellized (water soluble), Natural (9-cis beta carotene) is preferable to the synthetic form
Food sources Green leafy vegetables such as beet greens, collard greens, etc., carrots, peppers, squash, sweet potatoes, pumpkin, apricots, cantaloupe, peaches, etc.
Lab tests Serum carotene (only reveals current intake)
Drug interactions Beta-carotene is depleted by ingestion of Cholestyramine, Colchicine, Colestipol, Neomycin and Mineral Oil.
Nutrient interactions Generally thought to be synergistic.
Metabolism

Beta-carotene is split by intestinal enzymes into two molecules of Vitamin A. Being water-soluble, excess amounts are easily excreted.



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