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Pantothenic Acid

Proper name Pantothenic acid
Category Vitamin
Functions Forms Acetyl-Coenzyme A, essential to the creation of energy from carbohydrates via the Krebs cycle. Needed to form acetylcholine, the neurotransmitter that carries nerve signals from one nerve ending to the next. Also forms phospholipids needed for brain and nerve function. Detoxifies acetylaldehyde, a byproduct of alcohol metabolism. Required for the formation of steroid hormones and adrenal function. As such, it is valuable for treating the effects of stress. Aids in the formation of porphyrin in the hemoglobin of red blood cells. Relieves the symptom of burning feet in individuals with B5 deficiency.
RDA None stated but estimated intake is 5-10 mg per day in the average American diet.
Therapeutic dose As high as 1,500 mg per day in treatment of gout.
Deficiency symptoms Frank deficiency is rare as it is present in a wide variety of foods. B5 is helpful in the treatment of gout, chronic fatigue, adrenal exhaustion, improving athletic performance, and detoxification of acetylaldehyde.
Toxicity None known. High doses may cause diarrhea.
Best forms  Acetyl coenzyme A
Food sources Widely distributed in foods. Among the highest sources are liver, avocado and egg yolks.
Lab tests Microbiological assay
Drug interactions None known.
Nutrient interactions Works well with other nutrients, especially other B vitamins.
Metabolism

Readily absorbed in the intestines, it combines with phosphorus to become acetyl coenzyme A. It is widely distributed in the body.



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