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| Proper name |
Riboflavin |
| Category |
Vitamin |
| Functions |
Riboflavin facilitates the metabolism of carbohydrates, proteins and fats
by catalyzing oxidation-reductions reactions. It is essential for the production
of energy (ATP) within the mitochondria of the cell. Riboflavin is an anti-oxidant
and is part of another antioxidant, glutathione reductase. Necessary for
growth and reproduction, especially of the skin, hair and nails |
| RDA |
1.7 mg per day. |
| Therapeutic
dose |
15-100 mg per day. |
| Deficiency symptoms |
Physical signs include cracks in the corners of the mouth (Chelosis), beefy
red to magenta-colored tongue, reddening of the eyes and dry, itchy, scaly
skin, seborrheic dermatitis and eczema of the face and genitals. Burning
and itching of the eyes, soreness and burning of the mouth, lips and tongue.
Severe, long-term deficiency can cause nerve damage, depression and hysteria. |
| Toxicity |
No
known toxicity. |
| Best
forms
|
Riboflavin Ô5' Phosphate. |
| Food
sources |
Highest concentrations are found in Brewer's yeast, liver, milk, dairy products.
Lower concentrations are found in dark green vegetables, eggs, avocados,
oysters, mushrooms, salmon and tuna. Riboflavin is heat stable but degraded
by light. |
| Lab
tests |
Microbiological assay |
| Drug
interactions |
Riboflavin
is depleted by antibiotics such as, Penicillins, Cephalosporins, Fluoroquinolones,
Macrolides, Aminoglycosides, Sulfonamides, Tetracyclines, psychotherapeutics
such as Tricyclic antidepressants and Phenothiazines (Thorazine, Mellaril)
and oral contraceptives. |
| Nutrient interactions |
Works well with other nutrients, especially other B vitamins. |
| Metabolism |
Absorbed in the upper
part of the small intestine, it should be taken with food for better absorption.
Riboflavin is a water-soluble pigment that is poorly stored in the body.
It gives the urine a bright yellow color when excreted.
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